During the course of the eleven year series, America the Beautiful Quarters were released at a rate of five different designs per year with a single design released in the final year. The order of release for the coins was determined based on the order in which the national sites featured on the coins were federally designated. For the first few years of the program, an official launch ceremony was held at the site around the date the coins were released into circulation.
The first America the Beautiful Quarter featuring Hot Springs National Park of Arkansas was released on January 26, 2010. This was followed by the four additional releases for the year at roughly equal intervals. A similar schedule was followed for subsequent releases of the series, culminating with the final coin featuring Tuskegee Airmen National Historic Site of Alabama released on January 4, 2021.
As was the case for the previous State Quarters Program, the constant stream of new designs kept Americans watching their pocket change for the newest releases. A multitude of numismatic products were also released in coordination with the circulation release, providing collectors with many options to supplement their collections.
| 2010 America the Beautiful Quarters | |
| Hot Springs National Park Quarter | January 26, 2010 |
| Yellowstone National Park Quarter | April 1, 2010 |
| Yosemite National Park Quarter | June 6, 2010 |
| Grand Canyon National Park Quarter | August 20, 2010 |
| Mount Hood National Forest Quarter | November 15, 2010 |
| 2011 America the Beautiful Quarters | |
| Gettysburg National Military Park Quarter | January 24, 2011 |
| Glacier National Park Quarter | April 4, 2011 |
| Olympic National Park Quarter | June 13, 2011 |
| Vicksburg National Military Park Quarter | August 29, 2011 |
| Chickasaw National Recreation Area Quarter | November 14, 2011 |
| 2012 America the Beautiful Quarters | |
| El Yunque National Forest Quarter | January 23, 2012 |
| Chaco Culture National Historical Park Quarter | April 2, 2012 |
| Acadia National Park Quarter | June 11, 2012 |
| Hawaii Volcanoes National Park Quarter | August 27, 2012 |
| Denali National Park and Preserve Quarter | November 5, 2012 |
| 2013 America the Beautiful Quarters | |
| White Mountain National Forest Quarter | January 28, 2013 |
| Perry’s Victory and International Peace Memorial Quarter | April 1, 2013 |
| Great Basin National Park Quarter | June 10, 2013 |
| Fort McHenry National Monument Quarter | August 26, 2013 |
| Mount Rushmore National Memorial Quarter | November 4, 2013 |
| 2014 America the Beautiful Quarters | |
| Great Smoky Mountains National Park Quarter | January 27, 2014 |
| Shenandoah National Park Quarter | March 31, 2014 |
| Arches National Park Quarter | June 9, 2014 |
| Great Sand Dunes National Park and Preserve Quarter | August 25, 2014 |
| Everglades National Park Quarter | November 3, 2014 |
| 2015 America the Beautiful Quarters | |
| Homestead National Monument of America Quarter | February 9, 2015 |
| Kisatchie National Forest Quarter | April 13, 2015 |
| Blue Ridge Parkway Quarter | June 8, 2015 |
| Bombay Hook National Wildlife Refuge Quarter | September 14, 2015 |
| Saratoga National Historical Park Quarter | November 16, 2015 |
| 2016 America the Beautiful Quarters | |
| Shawnee National Forest Quarter | February 1, 2016 |
| Cumberland Gap National Historical Park Quarter | April 4, 2016 |
| Harpers Ferry National Historical Park Quarter | June 6, 2016 |
| Theodore Roosevelt National Park Quarter | August 29, 2016 |
| Fort Moultrie Quarter | November 14, 2016 |
| 2017 America the Beautiful Quarters | |
| Effigy Mounds National Monument Quarter | February 6, 2017 |
| Frederick Douglass National Historic Site Quarter | April 3, 2017 |
| Ozark National Scenic Riverways Quarter | June 5, 2017 |
| Ellis Island Quarter | August 28, 2017 |
| George Rogers Clark National Historical Park Quarter | November 13, 2017 |
| 2018 America the Beautiful Quarters | |
| Pictured Rocks National Lakeshore Quarter | February 5, 2018 |
| Apostle Islands National Lakeshore Quarter | April 9, 2018 |
| Voyageurs National Park Quarter | June 11, 2018 |
| Cumberland Island National Seashore Quarter | August 27, 2018 |
| Block Island National Wildlife Refuge Quarter | November 13, 2018 |
| 2019 America the Beautiful Quarters | |
| Lowell National Historical Park Quarter | February 4, 2019 |
| American Memorial Park Quarter | April 1, 2019 |
| War in the Pacific National Historical Park Quarter | June 3, 2019 |
| San Antonio Missions National Historical Park Quarter | August 26, 2019 |
| Frank Church–River of No Return Wilderness Quarter | November 4, 2019 |
| 2020 America the Beautiful Quarters | |
| National Park of American Samoa Quarter | February 13, 2020 |
| Weir Farm National Historic Site Quarter | April 6, 2020 |
| Salt River Bay National Historical Park Quarter | June 1, 2020 |
| Marsh-Billings-Rockefeller National Historical Park Quarter | August 31, 2020 |
| Tallgrass Prairie National Preserve Quarter | November 16, 2020 |
| 2021 America the Beautiful Quarters | |
| Tuskegee Airmen National Historic Site Quarter | January 4, 2021 |
